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Accumulation of uraemic toxins is reflected only partially by estimated GFR in paediatric patients with chronic kidney disease

Pediatric Nephrology Jan 18, 2018

Snauwaert E, et al. - This study involves accuracy test of estimated glomerular filtration rate (eGFR) for predicting the concentration of uraemic toxins in a paediatric chronic kidney disease (CKD) cohort. eGFR was found to be a poor predictor of concentrations of protein-bound uraemic toxins, uric acid [UA] and asymmetric dimethylarginine [ADMA] in childhood CKD, instead it only partially indicated the complexity of the accumulation pattern of uraemic toxins in childhood CKD.
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