Cauley JA, et al. - Researchers investigated if accelerated bone loss (ABL) shown on routine dual-energy X-ray absorptiometry (DXA) is accompanied by microarchitectural changes, increased cortical porosity, and lower bone strength. In this cross-sectional study, they analyzed 1628 men who attended the year 14 exam of the Osteoporotic Fractures in Men (MrOS) study. Outcomes indicated lower estimated bone strength, poorer trabecular microarchitecture, and thinner cortices among men with ABL than men without ABL. However, the groups showed similar cortical porosity. These impairments might result in an increased risk of fracture.