Narvid J, et al. - Researchers analyzed CBF data retrospectively and classified 19 HIV-infected (HIV+) older cases with plasma viral suppression (including 5 with the HIV-associated neurocognitive disorder) to analyze the distinct regional pattern of CBF abnormalities using quantitative whole-brain arterial spin-labeling. They observed alterations in regional cerebral perfusion, including hypoperfusion of bilateral temporal, parietal, and occipital brain fields compared to both clinically healthy subjects and those with mild cognitive impairment when estimated for age, education, sex, and vascular risk factors. They found consistent test characters in identifying those with the HIV-associated neurocognitive disorder from healthy controls and cases with mild cognitive impairment by using arterial spin labeling.