Gupta L, et al. - Whether abnormalities in spontaneous blood oxygen level-dependent fluctuations arise in focal cortical dysplasia lesions and proximal regions was assessed in this analysis. Participants in the study were 14 patients with focal cortical dysplasia-related epilepsy and 16 healthy controls. Structural and resting-state functional MR imaging was conducted in these participants. From the radiologically visible boundary, abnormalities in spontaneous blood oxygen level-dependent fluctuations were seen up to 2 cm distant. Study results showed that functional boundaries go beyond structural boundaries of focal cortical dysplasia lesions. However, validation was needed to reveal whether this information was valuable for surgical planning and outcome evaluation of focal cortical dysplasia lesions and comparing current results with electrophysiologic analysis.