Giampiero F, et al. - In this retrospective study, the researchers intended to describe the clinical impact of contrast-enhanced ultrasound (CEUS) as a guidance technique for ablation of primary and secondary liver tumors at six interventional ultrasound centers. During the period 2008-2016, one hundred forty-eight patients (103 M/45 F, median age 74 yrs.) with 151 liver target lesions (median size 15 mm, 86.7% Hepatocellular Carcinomas) in whom CEUS guidance was used for Percutaneous Ethanol Injection (35.2%), Radiofrequency (46.3%) and Microwave (18.5%) were selected. Data reported that CEUS guidance showed improved visibility and effectiveness in aiding ablation procedures that were otherwise technically troublesome using only B-Mode US guidance.