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Abdominal surgery in patients with idiopathic noncirrhotic portal hypertension: A multicenter retrospective study

Hepatology May 30, 2019

Elkrief L, et al. - In this multicenter retrospective study, researchers sought to analyze data on morbidity and mortality of abdominal surgery in patients with idiopathic noncirrhotic portal hypertension (INCPH). For this investigation, 44 subjects have been included with biopsy-proven INCPH. Within 3 months after surgery, extrahepatic conditions related to INCPH and history of ascites were linked to portal hypertension-related complications. After surgery, splenectomy was related to portal vein thrombosis development. Findings suggested no association of portal decompression procedures prior to surgery with postoperative outcome. Overall, the authors concluded that patients with INCPH are at high risk of major complications related to surgery and portal hypertension when they have INCPH-related extrahepatic conditions, history of ascites, or increased serum creatinine.
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