Abdominal radical trachelectomy vs chemotherapy followed by vaginal radical trachelectomy in stage 1B2 (FIGO 2018) cervical cancer. A systematic review on fertility and recurrence rates
Gynecologic Oncology Dec 13, 2019
van Kol KGG, et al. - Women with cervical cancer stage IB2 treated with either neoadjuvant platinum-based chemotherapy (NACT) followed by vaginal radical trachelectomy (VRT), or abdominal radical trachelectomy (ART) were compared regarding rates of fertility, pregnancy, live births as well as recurrence. Searching the PubMed database, researchers identified ten studies with a total of 338 patients for inclusion. After NACT followed by VRT vs ART, 39% and 40% of the women, respectively, tried to conceive; pregnancy was reported in 70% vs 21%, respectively; of these, 63% and 42%, respectively, resulted in a live birth. NACT followed by VRT and the ART group had equal number of recurrences and the mortality rate.
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