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Abdominal fat distribution in diffuse idiopathic skeletal hyperostosis and ankylosing spondylitis patients compared to controls

Clinical Radiology Jul 23, 2018

Dan Lantsman C, et al. - In the present study, the researchers assessed abdominal fat distribution (subcutaneous adipose tissue [SAT] and visceral adipose tissue [VAT]) in two enthesopathy-related diseases with known correlation to metabolic syndrome (MS): diffuse idiopathic skeletal hyperostosis (DISH) and ankylosing spondylitis (AS) compared with controls. They found that the higher VAT surface area (a known marker for MS) which by itself was correlated with bone proliferation. Data reported that in DISH and AS subjects compared to controls substantiates its role as a potential surrogate marker for MS. In addition, they suggests a potential shared pathogenic pathway for enthesopathic excessive bone production in DISH and AS.
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