Watson LE, et al. - In people with type 2 diabetes (T2DM), researchers assessed the impacts of 12 weeks of treatment with a whey/guar preload on gastric emptying, postprandial glycaemia and glycated haemoglobin (HbA1c) levels. A total of 79 people with T2DM treated with diet or metformin (HbA1c 49 ± 0.7 mmol/mol [6.6 ± 0.1%]) were randomized to receive 150 mL of flavoured preloads, containing either 17 g whey protein plus 5 g guar (n = 37) or flavoured placebo (n = 42), 15 minutes before two meals, for 12 weeks each day. In patients with well-controlled T2DM, 12-week treatment with low-dose whey/guar preload, taken twice a day before meals, had sustained effects of slowing down gastric emptying and decreasing postprandial blood glucose, which was related to a modest decrease in HbA1c without weight gain.