Ghazaleh HA, et al. - A systematic review was conducted to identify studies that analyzed insulin-related lipohypertrophy (LH) using ultrasound (US) detection to identify the prevalence, characteristics and morphology of LH, as well as to compare US and clinical palpation methods for identifying LH. For studies detecting LH using US in insulin users, 3 electronic databases were systematically searched. Identified risk factors for the development of included insulin injection behaviour, for example, a lack of injection site rotation and social factors like low education level. This investigation highlighted a lack of congruence in outcomes pertaining to the detection sensitivity of US and palpation for LH sites.