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A subclinical high tricuspid regurgitation pressure gradient independent of the mean pulmonary artery pressure is a risk factor for the survival after living donor liver transplantation

BMC Gastroenterology May 20, 2018

Saragai Y, et al. - In this investigation, the researchers retrospectively analyzed 84 living donor liver transplantation (LDLT) candidates to investigate the impact of a subclinical high tricuspid regurgitation pressure gradient (TRPG) on the survival of small grafted LDLT. Results of this study suggested that mean pulmonary artery pressure measured after general anesthesia with FIO20.6 (mPAP-FIO20.6) cannot accurately reflect the congestive pressure to the liver, as the pressure could escape via pulmonary shunt in cirrhosis patients. They discovered that a subclinical high TRPG was an important marker for predicting a worse survival after LDLT, possibly reflecting congestive pressure to the grafted small liver.
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