Ghosh A, Gupta S, Johny D, et al. - Researchers sought to assess anatomic and volumetric alterations in the parotid glands and tumour volume of head and neck cancers (HNC) patients receiving intensity modulated radiotherapy with simultaneous integrated boost (IMRT-SIB), as well as the dosimetric impact of these changes on dose variation to the target volume and parotid glands. The authors treated 30 patients with stage II–IV head and neck squamous cell carcinoma with definitive IMRT-SIB and concurrent chemotherapy. A significant correlation was found between a decrease in the patient's weight with a decrease in volume of both the parotid glands as well as the medial shift of the parotid gland which received a higher mean dose at initial planning. Wherever possible, adaptive IMRT would be helpful radiation dose delivery if the PTV and normal anatomy change over time.