Khurana RN, Hoang C, Khanani AM, et al. - In this prospective, multicenter reliability analysis, experts aspired to explore whether a mobile application, Checkup Vision Assessment System (Checkup; Verana Health, San Francisco, CA), can reliably monitor visual acuity (VA) and metamorphopsia remotely vs standard VA reference tests in the clinic. Participants in the study were patients (N = 108) with near corrected VA better than 20/200 and a diagnosis of age-related macular degeneration, diabetic retinopathy or healthy patients without retinal disease (best corrected visual acuity [BCVA] 20/32 or better). For VA and Amsler grid, there was strong agreement between Checkup and in-clinic tests. Checkup testing's low variance, agreement between in-clinic and home results, and excellent usability support Checkup as a reliable method for monitoring retinal pathology in the clinic and at home.