de Winter RJ, et al. - Comparison of the clinical effect of MiStent sirolimus-eluting stent with a durable polymer drug-eluting stents has been performed in a randomised, single-blind, multicentre, phase 3 trial. Based on the findings, the sirolimus-eluting bioabsorbable polymer stent proved non-inferior to the everolimus-eluting durable polymer stent for a device-oriented composite clinical endpoint at 12 months in an all-comer population. In clinical practice, MiStent appeared a reasonable alternative to other stents.