Peri M, et al. - In one of the largest, single-center, series of metastatic broncho-pulmonary neuroendocrine tumors (bpNETs), researchers studied disease, patient, and treatment characteristics by retrospectively analyzing cases of bpNETs and distant metastases (metachronous or synchronous), evaluated at the European Institute of Oncology between 1997 and 2014. Heterogeneity was revealed in the pattern of recurrences and the follow-up exams among patients with metachronous metastases. Most common sites of relapse were liver (67%), lymph node (25%), bone (22%) and lung (16%), and the most common tool used to detect first recurrence was computed tomography. A significant correlation of age, bone metastases, liver metastases and Ki-67 as a continuous variable, with prognosis was indicated in the multivariate analysis.