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A single-center retrospective cohort analysis of maternal and infant outcomes in HIV-infected mothers treated with integrase inhibitors during pregnancy

Infectious Diseases and Therapy Sep 19, 2017

Mounce ML, et al. - This study aimed to determine the differences in maternal and infant outcomes in HIV-positive mothers treated with Integrase strand transfer inhibitors (INSTI)-containing antiretroviral therapy (ART) during pregnancy compared to protease inhibitor (PI)-containing ART. Findings revealed no differences regarding efficacy or safety between patients treated with INSTIs compared to PIs. Further investigation of the use of INSTIs during pregnancy to reduce HIV transmission was recommended.
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