Tapper EB, et al. - A population-based cohort of all patients with cirrhosis without baseline hepatic encephalopathy (HE) from the Veterans Administration from Michigan, Indiana, and Ohio (January 1, 2005-December 31, 2010) using demographic, clinical, laboratory, and pharmacy data was studied to develop a tool to risk-stratify patients for HE development. Results of this study suggested that patients with cirrhosis could be stratified by a simple risk score for HE that accounts for changing clinical data. In addition, the data highlighted a role for statins in decreasing cirrhosis complications including HE.