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A retrospective, descriptive study of patients with mycosis fungoides treated by phototherapy (oral PUVA, NB‐UVB) with a twice‐weekly regimen at the Institute of Dermatology, Bangkok, Thailand, with an experiential timeline of 13 years

Photodermatology, Photoimmunology and Photomedicine Sep 26, 2020

Pattamadilok B, et al. - Researchers conducted the study for analyzing the initial clinical responses and time to relapse in patients with early‐stage mycosis fungoides (MF) treated with oral 8‐methoxypsoralen plus ultraviolet A (oral PUVA) and narrow‐band ultraviolet B (NB‐UVB) at a twice‐weekly regimen. Records of patients with biopsy‐proven MF who received oral‐PUVA or NB‐UVB in 2002–2014 were reviewed. Among 70 patients, 14 and 56 were treated, respectively, with oral‐PUVA and NB‐UVB. It was noted that the majority had early‐stage MF. With oral PUVA and NB-UVB, patients with early stage MF can achieve clinical response with a twice-a-week regimen. Findings revealed that the initial relapse‐free interval was longer than 1 year.

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