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A randomized, triple‐blind, placebo‐controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity

Journal of Cosmetic Dermatology Feb 24, 2021

Evans M, Lewis ED, Zakaria N, et al. - Researchers conducted this randomized, triple‐blind, placebo‐controlled study to assess the clinical benefits of a 12‐week supplementation of a fish‐derived collagen peptide on skin wrinkles and elasticity and self‐reported skin appearance in women between 45 and 60 years of age. Using the VISIA skin analysis system, Cutometer, and Skin Quality Visual Analogue Scale, assessments of skin wrinkles, elasticity, and self‐reported appearance were conducted. Participants supplemented with VWC after 12 weeks had a significant 35% decline in wrinkle score from baseline. A planned subgroup analysis based on age revealed women 45‐54 years had a significant 20% and 10% improvement in cheek skin elasticity from baseline to week 6 and 12, respectively. Supplementation with VWC has been observed to be safe and well‐tolerated. The findings of this study support the use of fish‐derived hydrolyzed collagen for improving skin health in an aging population.

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