Rodriguez J, et al. - Experts tested dendritic cell vaccines loaded with autologous tumor lysates for their potential to avoid or delay disease relapses of surgically resectable synchronic and metachronic liver metastases of colon cancer. Fifteen patients with disease-free resection margins were randomly allocated 1:1 to receive two courses of four daily doses of dendritic cell intradermal vaccinations vs observation. In the vaccine arm, a clear inclination for fewer and later relapses was seen vs the observation arm in the follow-up, which illustrates the potential of DC vaccinations with autologous tumor antigens for patients with colon cancer liver metastasis amenable to complete surgical resections.