Caltagirone R, et al. - In a randomized controlled trial, researchers compared a needle-free jet-injection system (J-Tip) with 1% buffered lidocaine to topical anesthetic (TA) cream for local anesthesia in infant Lumbar punctures (LPs). Among the two modalities for local anesthesia in infant LPs, J-Tip was identified not to be superior to TA cream as measured by pain control or physiologic changes. Infant LPs performed with J-Tip were twice as likely to be successful.