A-Tjak JGL, et al. - In this study, acceptance and commitment therapy (ACT) was compared with cognitive behavioral therapy (CBT) for depression, testing the hypothesis that CBT would outperform ACT. Results indicated that in treating depression, CBT was not more effective than ACT. Patients in both conditions reported significant and large reductions in depressive symptoms and improvement in quality of life from before to after treatment as well as at the follow-up.