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A randomized controlled trial comparing the myocardial protective effects of isoflurane with propofol in patients undergoing elective coronary artery bypass surgery on cardiopulmonary bypass, assessed by changes in N-terminal brain natriuretic peptide

Annals of Cardiac Anaesthesia Jan 17, 2018

Kuppuswamy B, et al. - In patients undergoing elective coronary artery bypass surgery on cardiopulmonary bypass (CPB), researchers assessed changes in N-terminal brain natriuretic peptide (NT proBNP) to gain insight into myocardial protective effects of isoflurane vs propofol. In this population, myocardial protective effect displayed by propofol was found to be comparable to that of isoflurane. At least in patients with good left ventricular function, propofol may be the ideal alternative to volatile anesthetics given the unproven mortality benefit of isoflurane and the improved awareness of green OT concept.
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