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A randomized controlled trial comparing colonoscopic enema with additional oral preparation as a salvage for inadequate bowel cleansing before colonoscopy

Journal of Clinical Gastroenterology Aug 14, 2019

Yang HJ, Park D, Park SK, et al. - In this prospective, randomized, actively-controlled, parallel group, noninferiority trial involving 131 candidates, researchers assessed the noninferiority of colonoscopic enema to additional oral preparation in salvage bowel cleansing for inadequate preparation for a morning colonoscopy. For this investigation, consecutive outpatients and health checkup recipients (aged 19 to 70 years) with inappropriate bowel preparation during an elective colonoscopy were recruited to receive either a colonoscopic enema of 1 L polyethylene glycol (PEG) (enema group) or additional oral intake of 2 L PEG (oral group). Using the Boston Bowel Preparation Scale, the primary endpoint was the proportion of adequate bowel preparation assessed. In adults with inadequate bowel cleansing for colonoscopy, the colonoscopic enema of 1 L PEG was lower than the additional oral ingestion of 2 L PEG with regard to efficacy as a salvage bowel preparation. In the right colon, the largest difference in the proportion of adequate bowel preparation was seen, followed by the transverse colon and the left colon.
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