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A randomized comparison of three prandial insulin dosing algorithms for children and adolescents with Type 1 diabetes

Diabetic Medicine Jun 24, 2018

Lopez PE, et al. - A randomized, crossover trial was performed at two Paediatric Diabetes centres to compare systematically the impact of two novel insulin-dosing algorithms (the Pankowska Equation and the Food Insulin Index) with carbohydrate counting on postprandial glucose excursions following a high fat and a high protein meal. Researchers reported that the Pankowska Equation resulted in decreased postprandial hyperglycaemia at the expense of an increase in hypoglycaemia. No significant differences were found when carbohydrate counting was compared to the Food Insulin Index.
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