Dooms C, et al. - In this single-center, randomized, controlled trial involving patients with suspected lung cancer, researchers assessed quantitative and qualitative specimen characteristics of flexible 19-gauge (Flex 19G) needle for endobronchial ultrasonography. Using a computer-generated randomization, patients were assigned 1: 1 to undergo endobronchial ultrasonography using a Flex 19G or a 22-gauge (22G) needle for lymph node tissue sampling. They mainly looked for histological tissue core procurement as well as for diagnostic yield, specimen bloodiness and overall quality, tissue surface area and performance for next-generation sequencing (NGS), and procedure-related complications. They found that Flex 19G was not superior with regards to histological tissue core procurement rate. In cases where a larger tissue surface was of special interest, the Flex 19G needle could be considered.