de Castro Junior G, et al. - This study was designed to determine the safety and efficacy of chemoradiation combined with nimotuzumab, a humanised antibody directed against epidermal growth factor receptor (EGFR), in locally advanced oesophageal cancer. Findings revealed safety of combined chemoradiotherapy plus nimotuzumab. It seemed increasing the endoscopic complete response as well as pathologic complete response rate, without compromising quality of life.