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A randomised controlled trial of the pectoral nerves -2 (PECS-2) block for radical mastectomy

Anaesthesia Jul 10, 2019

Al Ja'bari A, et al. - Researchers sought for a cumulative 24-h postoperative morphine dose among women scheduled for a radical mastectomy who were randomly allocated to pectoral nerves-2 (PECS-2) block or no block. Intra-operative sufentanil, magnesium, dexamethasone and droperidol were provided. They administered regular postoperative paracetamol, ibuprofen and patient-controlled intravenous morphine to the participants. Outcomes revealed a reduction in mean (SD) cumulative 24 h postoperative morphine dose from 9.7 (8.9) mg to 5.0 (5.4) mg and 48 h morphine dose from 12.8 (12.5) mg to 6.0 (6.5) mg in correlation to pectoral nerves-2 block. Similar mean (SD) pain scores 24 h and 48 h after surgery were evident with or without block. At six postoperative months, rates of chronic pain after block and no block were 2/19 and 2/18, respectively.
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