Chen W, Shen J, Zhang Y, et al. - A randomized controlled trial was designed to evaluate fibrinogen concentrate during scoliosis surgery. Researchers randomized 102 children 12–18 years old having surgery for idiopathic scoliosis, 51 to intra‐operative fibrinogen concentrate 30 mg.kg−1 (maximum 2 g) and 51 to saline placebo. It was shown that fibrinogen decreased peri‐operative blood loss by a median (95%CI) volume of 155 (5–320) ml, from a median (IQR [range]) of 1035 (818–1420 [400–3030]) ml to 885 (755–1155 [270–2645]) ml, p = 0.04. It was noted that They administered allogeneic red blood cell transfusion to seven and four children after fibrinogen and placebo, respectively, p = 0.34. No side‐effects were reported.