A prospective study of reproductive factors in relation to risk of systemic lupus erythematosus among black women
Lupus Nov 27, 2020
Cozier YC, et al. - As most commonly reproductive age women are affected by systemic lupus erythematosus (SLE), suggesting a potential role of reproductive factors, researchers here examined the correlations between reproductive factors and SLE risk among black women. Using biennial health questionnaires, 58,243 participants in the Black Women’s Health Study (BWHS) were followed from 1995 – 2015, on which participants reported reproductive and other factors. Among these patients, 125 incident cases of SLE were confirmed during 954,476 person-years of follow-up. Findings suggest increased SLE risk among black women in correlation with later menarchal age and breastfeeding of infants for ≥ 6 months vs none. Further study is required to determine the biological mechanisms underlying these potential associations.
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