Zhang Y, Zhou CK, Rencsok EM, et al. - Given a common occurrence of inflammation and focal atrophy adjacent to prostate tumors, researchers examined the prognostic significance of these features. In the Health Professionals Follow-Up Study and Physicians’ Health Study, 1,035 men diagnosed with prostate cancer were studied. Tumor and normal areas of hematoxylin and eosin slides from prostate cancer specimens were centrally reviewed by a genitourinary pathologist for the presence of acute and chronic inflammation, and four subtypes of focal atrophy. Lethal prostate cancer developed in 153 men during a median of 12 years of follow-up. Histologic evidence of chronic inflammation was present in a total of 84% of men and acute inflammation was present in 30% of men. As per data gained, the presence of inflammation, particularly chronic inflammation, in prostate cancer tissue seems to be correlated with better prognosis among these patients.