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A prospective study evaluating the impact of implementing ‘bundled interventions’ in reducing surgical site infections among patients undergoing surgery for gynaecological Malignancies

European Journal of Obstetrics & Gynecology and Reproductive Biology Nov 24, 2019

Agarwal, R, et al. - Researchers examined how 30-day surgical site infection (SSI) rate affected following the introduction of evidence-based "bundled interventions" (BI) in gynaecological malignancy (GM). They performed a prospective interventional study at a Single University teaching hospital including 840 patients. Of these, 624 underwent laparotomy before (PRE) the implementation of BI and 216 after the implementation. Ovarian cancer (OC) was the most common diagnosis. Following the implementation of BI, they observed a significant reduction in: overall and superficial SSI rates; OC undergoing surgery without bowel resection (BR); and OC with BR. Deep organ/space infections or readmissions during the postintervention period were not observed in any of the patients. Findings indicate an association of implementation of BI with a significant reduction of SSI rate in GM. Further, the intervention was identified as effective in at-risk patients with non-modifiable clinico-pathologic and surgical factors.
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