Koyama K, et al. – In this study, researchers investigated whether automated coregistration of optical coherence tomography (OCT) with angiography reduces geographic miss (GM) during coronary stenting. They evaluated 200 de novo coronary lesions. These lesions were randomized (1:1) to OCT-guided percutaneous coronary intervention (PCI) with vs without automated coregistration of OCT with angiography. The primary endpoint was GM, which was considered to be angiographic ≥ type B dissection or diameter stenosis > 50% or OCT minimum lumen area < 4.0 mm² with significant residual disease or dissection (dissection flap >60°) within 5 mm from the stent edge. According to the findings, the primary endpoint of GM after stent implantation was not attenuated by the automated coregistration of OCT with angiography.