Ishigaki K, Nakai Y, Sasahira N, et al. - Researchers conducted this multicenter prospective study to perform per pass and semi-quantitative analyses of endoscopic ultrasound (EUS)‐guided fine‐needle biopsy (EUS‐FNB) using the 22-gauge Franseen needle in patients with pancreatic solid lesions. Cytological and histological analyses per pass were assessed and semi‐quantitative analyses were conducted on core tissue and blood contamination. In total, 629 passes were conducted in 244 cases at 14 centers between 2018 and 2019. In the multivariate analysis, tumor size ≤ 20 mm, transduodenal puncture, and suction were linked to lower diagnostic accuracy. For pancreatic solid lesions, the EUS‐FNB with the 22‐gauge Franseen needle demonstrated high per pass and overall diagnostic accuracy.