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A prospective comparison of dynamic contrast-enhanced MRI and 51Cr-EDTA clearance for glomerular filtration rate measurement in 42 kidney transplant recipients

European Journal of Radiology Feb 08, 2019

Taton B, et al. - Via prospectively studying 42 kidney transplant recipients (KTRs; mean age 51.5 years, 26 – 74) with an indication for non-urgent contrast-enhanced MRI between 2008 and 2012, researchers evaluated the performance of dynamic contrast-enhanced MRI measurement of glomerular filtration rate (GFR) compared with the reference standard technique of urinary clearance of 51Cr-EDTA. Outcomes revealed a large variability of MR-GFR compared with the reference technique. This prevents its use in KTRs, whose anatomical peculiarities make standardization of arterial input function (AIF) difficult.
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