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A prospective cohort study of condensed low dose total skin electron beam therapy for mycosis fungoides: Reduction of disease burden and improvement in quality of life

Journal of the American Academy of Dermatology Feb 01, 2020

Song A, Gochoco A, Zhan T, et al. - Researchers carried out a cohort study (2014-2018), with median follow-up of 22.8 months, to determine the safety and effectiveness of a novel, condensed low-dose total skin electron beam therapy (TSEBT) for mycosis fungoides (MF). Of 25 individuals, Stage IB was most common at the time of TSEBT. Data reported that overall response rate was 88%. A near complete response was most common. The median response duration was 17.5 months while the median response time was 2 months. QOL and disease burden demonstrated significant benefit post-TSEBT. Findings suggested that condensed, low-dose TSEBT has favorable results and toxicity with logistical convenience.
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