Chiu YH, et al. - Considering that circulating saturated (SFA) and monounsaturated fatty acids (MUFA) may influence non-Hodgkin lymphoma (NHL) risk by modulating inflammation or lymphocyte membrane stability, researchers evaluated NHL risk associated with these fats. They performed a prospective study of 583 incident NHL cases and 583 individually matched controls with archived pre-diagnosis red blood cell (RBC) specimens in the Nurses’ Health Study (NHS) and Health Professionals Follow-Up Study (HPFS). Findings revealed inverse associations for very long chain SFA levels (VLCSFAs) with B cell NHL other than chronic lymphocytic leukemia/small lymphocytic lymphoma and for VLCSFA and MUFA with T cell NHL (T-NHL). This indicates that fatty acid metabolism influences lymphomagenesis.