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A preliminary report on the effect of gabapentin pretreatment on periprocedural pain during in-office posterior nasal nerve cryoablation

International Forum of Allergy & Rhinology Nov 08, 2019

Steele TO, Hoshal SG, Kim M, et al. - In this multi-institutional prospective analysis involving 26 patients (gabapentin n = 15, control = 11), researchers assessed the impact of gabapentin on patient discomfort following in-office posterior nasal nerve (PNN) cryoablation, a novel surgical technique to address allergic and nonallergic rhinitis. Between March 2018 and April 2019, patients undergoing in-office PNN cryoablation for allergic or nonallergic rhinitis were included. Participants in the study received local anesthesia with or without 600 mg oral gabapentin 1 hour preprocedure. Findings suggested that preprocedure gabapentin significantly decreases the discomfort of the patient immediately and delayed after cryoablation of the PNN.
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