Antoniou T, et al. - In older men treated with dutasteride or finasteride, experts compared the risk of osteoporosis and fractures. A population-based retrospective cohort study was conducted with high-dimensional propensity score matching of Ontario men aged 66 years or older who started treatment with dutasteride or finasteride between January 1, 2006 and December 31, 2012. Findings did not suggest an association of dutasteride with an increased risk of osteoporosis or fractures in older men relative to finasteride, despite differential effects on 5-alpha reductase. As per data, no adverse impact of dutasteride on bone health was seen.