Saravu K, et al. - Researchers conducted a two centre, randomized, open-label, two arm study in South India to ascertain the operational effectiveness and optimum dosing of the currently recommended 14-day primaquine (PQ) course for the radical cure of vivax malaria. They randomized 50 patients to receive either high dose (0.5 mg base/kg body weight) or conventional dose (0.25 mg/kg) PQ for 14 days. As per outcomes, the currently recommended lower dose (0.25 mg/kg/day) 14 day PQ regimen is efficacious for the radical cure of vivax malaria in South India.