A novel risk score to predict early and late recurrence in solitary fibrous tumour
Histopathology Feb 06, 2020
Georgiesh T, et al. - Researchers intended to establish a prognostic model accounting for both early and late recurrences applying a relatively large individual cohort with long-term follow-up. The evaluation of clinicopathological factors in a cohort of 100 extrameningeal, STAT6-positive solitary fibrous tumours (SFTs) was conducted. For overall survival (OS) and recurrence-free interval (RFi), the median follow-up was 121 and 84 months, respectively. In 31% of patients, the occurrence of disease relapse was found and 63 months was the median time of recurrence. Necrosis and gender were independent prognostic markers of recurrence in this cohort of individuals with extrameningeal SFT and long-term follow-up mitotic count. They suggest a novel risk score based on these factors and estimating for late recurrences, which should be approved in external cohorts with sufficient follow-up time.
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