Truhn D, et al. - Researchers studied 16 subjects who experienced dynamic T1-weighted turbo gradient echo imaging at 1.5 T earlier and after bolus injection of gadoxetic acid at 0.1 ml/kg and their dynamic contrast-enhanced (DCE) images were obtained for 30 min after injection with the purpose to improve the assessment of hepatic synthetic function and provide quantitative measures of hepatic excretion function. They extracted 4 tissue parameters ie, extracellular volume fraction, arterial flow fraction, uptake rate and excretion half-time for each liver segment and a dual-inlet two-compartment model was then used to measure these parameters. They obtained less variation and improved fit quality for the dual-inlet two-compartment model with mean values for arterial flow fraction, extracellular volume and uptake rate comparable to those obtained with the conventional model.