Dondo TB, Hall M, Munyombwe T, et al. - In order to estimate the relative contribution of temporal shifts in treatments and patient characteristics on improved ST-elevation myocardial infarction (STEMI) survival, researchers performed this cohort study in 232,353 survivors of hospitalisation with STEMI from 247 hospitals in England and Wales, using national registry data from the Myocardial Ischaemia National Audit Project between first January 2004 and 30th June 2013. They noted improvements in unadjusted survival at 6 months and 1 year by 0.9% and 1.0% on average per year, during the study period. According to the findings, the uptake of primary percutaneous coronary intervention (PCI) and increased use of P2Y₁₂ inhibitors at 6 months and primary PCI only at 1 year significantly explained the observed improvements in survival between 2004 and 2013, for STEMI in England and Wales.