White PL, Dhillon R, Cordey A, et al. - Researchers investigated the incidence, risk factors and influence of invasive fungal disease in adult COVID-19 patients with severe respiratory distress. Among 135 screened adults (median age: 57, M/F: 2·2/1), they observed incidence of 26.7% (14.1% aspergillosis, 12·6% yeast infections). The overall mortality rate of 38% was reported, with 53% and 31% in patients with and without fungal disease, respectively. Observations thereby suggest frequent occurrence of fungal disease in critically ill, mechanically ventilated COVID-19 patients. Patients receiving antifungal therapy showed survival benefit indicating appropriateness of the proposed diagnostic and defining criteria. They suggest a possible utility of screening using a strategic diagnostic approach and antifungal prophylaxis of patients with risk factors in enhancing the management of COVID-19 patients.