Vilar E, Kamal RMK, Fotheringham J, et al. - Incremental hemodialysis affords a safe as well as cost-saving approach for incident patients with adequate residual kidney function.

• A randomized controlled feasibility trial in the United Kingdom.

• 55 incident hemodialysis patients with urea clearance of 3ml/min/1.73m ² or more were included.

• 26 patients received standard hemodialysis and 29 incremental hemodialysis.

• At 6 months, urea clearance of 2ml/min/1.73m ² or more was seen in 92% of incremental and 75% of standard arm patients.

• Incremental patients had less frequent occurrence of serious adverse events.

• Significantly lower serum bicarbonate was found in incremental patients.

• Significantly higher were median incremental hemodialysis costs vs incremental hemodialysis.