A multi‐centre, single‐blinded randomised controlled clinical trial evaluating the effect of resorbable glass fibre matrix in the treatment of diabetic foot ulcers
International Wound Journal Aug 27, 2021
Armstrong DG, Orgill DP, Galiano RD, et al. - Addition of a unique resorbable glass microfiber matrix (Mirragen; Advanced Wound Matrix [BBGFM]; ETS Wound Care, Rolla, Missouri) to standard of care (SOC, collagen alginate dressing) in the treatment of diabetic foot ulcers (DFUs) led to a significant improvement in wound healing with no adverse events related to treatment when compared with treating with SOC alone.
Seventy percent (14/20) of the BBGFM-treated DFUs healed compared with 25% (5/20) treated with SOC alone at 12 weeks.
In the BBGFM group, mean percent area reduction (PAR) was 79% vs 37% in the SOC group at 12 weeks.
The BBGFM vs SOC group showed mean change of 2.0 vs −0.6 in neuropathic score between baseline and up to 12 weeks of treatment where positive improvement in scores are better.
On average, 6.0 BBGFM applications were required.
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