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A meta-analysis on the surgical management of paraganglioma of the carotid body per Shamblin class

Clinical Otolaryngology Jun 14, 2018

Jansen TTG, et al. - Researchers assessed the risk related to different types of surgery for carotid body paraganglioma of different Shamblin class. They conducted a meta-analysis to evaluate per tumour class, the local control, cranial nerve damage and complication rates of different techniques using internal carotid artery (ICA) and external carotid artery (ECA) ligation, clamping or bypassing, as well as the craniocaudal vs caudocranial techniques. Surgery seemed to be a viable treatment option for class 1 and 2 tumours. Morbidity in terms of cranial nerve deficit and complications is considerable for class 3 tumours. Particularly, high stroke incidence was seen to be accompanied by the use of ICA manipulation/reconstruction and potentially ECA ligation.
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