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A meta-analysis on the global prevalence, risk factors and screening of coronary heart disease in non-alcoholic fatty liver disease

Clinical Gastroenterology and Hepatology Sep 25, 2021

Toh JZK, Pan XH, Tay PWL, et al. - The presence of steatosis has been correlated with coronary heart disease (CHD), with moderate to severe steatosis being related to clinical coronary artery disease (CAD). For holistic treatment in non-alcoholic fatty liver disease (NAFLD), early screening and rapid intervention for CHD are required.

  • The prevalence of clinical CAD was reported in 14 of the 38 publications, while subclinical CAD was recorded in 24.

  • CHD was found in 44.6% of 67,070 NAFLD patients, with an odds ratio of 1.33.

  • CHD was more common in patients with moderate to severe steatosis than in those with mild steatosis.

  • Subclinical and clinical CAD were shown to be prevalent in 38.7% and 55.4% of people, respectively.

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