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A lower level of forced expiratory volume in one second predicts the poor prognosis of small cell lung cancer

Journal of Thoracic Disease May 04, 2018

Kang HS, et al. - In this retrospective multicenter study, researchers investigated whether the parameters of impaired lung function are related to clinical outcomes in patients with small cell lung cancer (SCLC). For this purpose, they compared the clinical characteristics and prognosis of SCLC patients that were treated with chemotherapy and/or radiotherapy and grouped them into chronic obstructive pulmonary disease (COPD) group and non-COPD group. Between the COPD and non-COPD groups, no differences in the clinical characteristics and treatment strategies and no difference in overall survival (OS) was reported. A low forced expiratory volume in 1 second (FEV1), not COPD, was identified as a predicting factor for poor treatment outcomes in SCLC patients.
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