Leung KK, et al. - In this retrospective observational study, researchers evaluated the clinical utility of computed tomography enterography (CTE) and identified factors for patients with obscure gastrointestinal bleeding (OGIB) associated with CTE diagnosis. A total of 138 patients had an OGIB CTE. In 30 cases, a possible source of bleeding has been identified. In univariate and multivariate analyses, the presence of abdominal or constitutional symptoms as well as the history of colorectal cancer was significantly linked to a positive CTE. Based on the presence of abdominal or constitutional symptoms and history of colorectal cancer with 90% sensitivity in the population, a positive CTE could be predicted. In one in five cases, CTE identified a potential source of OGIB. CTE may contribute to their diagnostic work in patients with abdominal or constitutional symptoms and a personal history of colorectal cancer.